The Third Coast Workshop on Biological Cryo-EM

Max Pavlevsky Theater, Ida Noyes Hall, University of Chicago • March 3, 2017

7:45 Registration
8:30 Welcome and Intro

Session I (Eduardo Perozo, University of Chicago, Chair)

8:40 Robert Glaeser (University of California at Berkeley)
How much better we can expect cryo-EM to get, and what remains to be done
9:15 Pawel Penczek (University of Texas at Houston)
SPHIRE – a new single particle cryo-EM computational environment
9:50 Vera Moiseenkova-Bell (Case Western Reserve University)
Molecular insight into the structure and function of TRPV channels
10:25 Break 1 (25 minutes) (Vendor exhibits)

Session II (Valerie Tokars, Northwestern University, Chair)

10:50 Grant Jensen (California Institute of Technology)
Structural biology in vivo through electron cryotomography
11:25 Yuan He (Northwestern University)
Near-atomic resolution visualization of human transcription initiation
11:50 Elizabeth Villa (University of California at San Diego)
Opening Windows into the Cell: Revealing the Molecular Architecture of the Nuclear Periphery
12:25 Lunch (60 minutes) (Vendor exhibits)

Session III (Andrzej Joachimiak, Argonne National Laboratory, Chair)

1:25 Richard Kuhn (Purdue University)
Cryo-EM Studies Reveal Details on Zika Virus and Dengue Virus Biology
2:00 Nestor Zaluzec (Argonne National Library)
Opportunities in Hyperspectral Imaging and Wavefront Manipulation in Next Generation Instruments
2:25 Dorit Hanein (Sanford Burnham Prebys Medical Discovery Institute)
Nanoscale Characterization of Mammalian Cells Cytoskeleton; Quantitative Correlative Light and Electron cryo-Microscopy Study
3:00 Break 2 (25 minutes) (Vendor exhibits)

Session IV (Alfonso Mondragón, Northwestern University, Chair)

3:35 Tamir Gonen (HHMI Janelia Research Campus)
MicroED opens a new era for biological structure determination
4:10 Minglei Zhao (University of Chicago)
Atomic model refinement in single-particle cryo-electron microscopy
4:35 Ed Egelman (University of Virginia)
Cryo-EM of Helical Polymers at Near-Atomic Resolution and Insights into Evolutionary Divergence
5:10 Closing statements