MPSDC Publications: Complete List

Publications Directly from the Consortium

Last updated: June 2015

These publications reflect the broad goals and aims of the Bridges, Pilots, and Cores

CMC=Computational Modeling Core; PCC=Protein Production and Chemistry Core; SAB=Synthetic Antigen Binder Core, SIC=Spectroscopy and Instrumentation Core (from members of the new Spectroscopy and Instrumentation Core)

  1. T. Stuwe, A. R. Correia, D. H. Lin, M. Paduch, V. T. Lu, A. A. Kossiakoff and A. Hoelz. Nuclear pores. Architecture of the nuclear pore complex coat. Science. 2015;347(6226):1148-52. (sAB)
  2. A. Mateja, M. Paduch, H. Y. Chang, A. Szydlowska, A. A. Kossiakoff, R. S. Hegde and R. J. Keenan. Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo. Science. 2015;347(6226):1152-5. (sAB)
  3. Z. Li, A. S. Lee, S. Bracher, H. Jung, A. Paz, J. P. Kumar, J. Abramson, M. Quick and L. Shi. Identification of a second substrate-binding site in solute-sodium symporters. J Biol Chem. 2015;290(1):127-41. PubMed Central PMCID: PMC4281715. (Bridge 3)
  4. S. M. Islam and B. Roux. Simulating the Distance Distribution between Spin-Labels Attached to Proteins. J Phys Chem B. 2015;119(10). PubMed Central PMCID: PMC25645890. (CMC)
  5. D. J. Hardy, Z. Wu, J. C. Phillips, J. E. Stone, R. D. Skeel and K. Schulten. Multilevel Summation Method for Electrostatic Force Evaluation. J Chem Theory Comput. 2015;11(2):766-779. PubMed Central PMCID: PMC4325600. (CMC)
  6. N. Akyuz, E. R. Georgieva, Z. Zhou, S. Stolzenberg, M. A. Cuendet, G. Khelashvili, R. B. Altman, D. S. Terry, J. H. Freed, H. Weinstein, O. Boudker and S. C. Blanchard. Transport domain unlocking sets the uptake rate of an aspartate transporter. Nature. 2015;518(7537):68-73. PubMed Central PMCID: PMC4351760. (CMC, ex-Pilot 3)
  7. S. J. Abraham, R. C. Cheng, T. A. Chew, C. M. Khantwal, C. W. Liu, S. Gong, R. K. Nakamoto and M. Maduke. C NMR detects conformational change in the 100-kD membrane transporter ClC-ec1. J Biomol NMR. 2015. (Bridge 5, PCC)
  8. X. Zhou, E. J. Levin, Y. Pan, J. G. McCoy, R. Sharma, B. Kloss, R. Bruni, M. Quick and M. Zhou. Structural basis of the alternating-access mechanism in a bile acid transporter. Nature. 2014;505(7484):569-73. PubMed Central PMCID: PMC4142352. (Pilot 1)
  9. X. Zhang, R. Hoey, A. Koide, G. Dolios, M. Paduch, P. Nguyen, X. Wu, Y. Li, S. L. Wagner, R. Wang, S. Koide and S. S. Sisodia. A synthetic antibody fragment targeting nicastrin affects assembly and trafficking of gamma-secretase. J Biol Chem. 2014;289(50):34851-61. PubMed Central PMCID: PMC4263884. (SAB)
  10. E. L. Wu, X. Cheng, S. Jo, H. Rui, K. C. Song, E. M. Davila-Contreras, Y. Qi, J. Lee, V. Monje-Galvan, R. M. Venable, J. B. Klauda and W. Im. CHARMM-GUI Membrane Builder toward realistic biological membrane simulations. J Comput Chem. 2014;35(27):1997-2004. PubMed Central PMCID: PMC4165794. (CMC)
  11. M. Weingarth, E. A. van der Cruijsen, J. Ostmeyer, S. Lievestro, B. Roux and M. Baldus. Quantitative analysis of the water occupancy around the selectivity filter of a K+ channel in different gating modes. J Am Chem Soc. 2014;136(5):2000-7. (Bridge 4, CMC)
  12. Y. Wang, J. T. Paletta, K. Berg, E. Reinhart, S. Rajca and A. Rajca. Synthesis of unnatural amino acids functionalized with sterically shielded pyrroline nitroxides. Org Lett. 2014;16(20):5298-300. PubMed Central PMCID: PMC4201325. (PCC)
  13. Y. Wang, Y. Liu, H. A. Deberg, T. Nomura, M. T. Hoffman, P. R. Rohde, K. Schulten, B. Martinac and P. R. Selvin. Single molecule FRET reveals pore size and opening mechanism of a mechano-sensitive ion channel. Elife. 2014;3:e01834. PubMed Central PMCID: PMC3925968. (CMC)
  14. R. B. Stockbridge, A. Koide, C. Miller and S. Koide. Proof of dual-topology architecture of Fluc F- channels with monobody blockers. Nat Commun. 2014;5:5120. PubMed Central PMCID: PMC4265568. (sAB)
  15. Y. Qi, X. Cheng, W. Han, S. Jo, K. Schulten and W. Im. CHARMM-GUI PACE CG Builder for solution, micelle, and bilayer coarse-grained simulations. J Chem Inf Model. 2014;54(3):1003-9. PubMed Central PMCID: PMC3985889. (CMC)
  16. M. Moradi and E. Tajkhorshid. Computational Recipe for Efficient Description of Large-Scale Conformational Changes in Biomolecular Systems. J Chem Theory Comput. 2014;10(7):2866-2880. PubMed Central PMCID: PMC4089915. (CMC)
  17. S. Mondal, G. Khelashvili and H. Weinstein. Not just an oil slick: how the energetics of protein-membrane interactions impacts the function and organization of transmembrane proteins. Biophys J. 2014;106(11):2305-16. PubMed Central PMCID: PMC4052241. (CMC)
  18. S. Mondal, G. Khelashvili, N. Johner and H. Weinstein. How the dynamic properties and functional mechanisms of GPCRs are modulated by their coupling to the membrane environment. Adv Exp Med Biol. 2014;796:55-74. (CMC)
  19. S. Mishra, B. Verhalen, R. A. Stein, P. C. Wen, E. Tajkhorshid and H. S. McHaourab. Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter. Elife. 2014;3:e02740. PubMed Central PMCID: PMC4046567. (Bridge 2, CMC)
  20. R. McGreevy, A. Singharoy, Q. Li, J. Zhang, D. Xu, E. Perozo and K. Schulten. xMDFF: molecular dynamics flexible fitting of low-resolution X-ray structures. Acta Crystallogr D Biol Crystallogr. 2014;70(Pt 9):2344-55. PubMed Central PMCID: PMC4157446. (CMC, PCC)
  21. Q. Li, S. Wanderling, M. Paduch, D. Medovoy, A. Singharoy, R. McGreevy, C. A. Villalba-Galea, R. E. Hulse, B. Roux, K. Schulten, A. Kossiakoff and E. Perozo. Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain. Nat Struct Mol Biol. 2014;21(3):244-52. PubMed Central PMCID: PMC4116111. (Bridge 4, CMC, sAB)
  22. M. V. LeVine and H. Weinstein. NbIT–a new information theory-based analysis of allosteric mechanisms reveals residues that underlie function in the leucine transporter LeuT. PLoS Comput Biol. 2014;10(5):e1003603. PubMed Central PMCID: PMC4006702. (Bridge 3, CMC)
  23. K. Kazmier, S. Sharma, M. Quick, S. M. Islam, B. Roux, H. Weinstein, J. A. Javitch and H. S. McHaourab. Conformational dynamics of ligand-dependent alternating access in LeuT. Nat Struct Mol Biol. 2014;21(5):472-9. PubMed Central PMCID: PMC4050370. (Bridge 3, CMC)
  24. K. Kazmier, S. Sharma, S. M. Islam, B. Roux and H. S. McHaourab. Conformational cycle and ion-coupling mechanism of the Na+/hydantoin transporter Mhp1. Proc Natl Acad Sci U S A. 2014;111(41):14752-7. PubMed Central PMCID: PMC4205665. (Bridge 3, CMC)
  25. R. E. Hulse, J. R. Sachleben, P. C. Wen, M. Moradi, E. Tajkhorshid and E. Perozo. Conformational dynamics at the inner gate of KcsA during activation. Biochemistry. 2014;53(16):2557-9. PubMed Central PMCID: PMC4010282. (Bridge 4)
  26. W. Han, R. C. Cheng, M. C. Maduke and E. Tajkhorshid. Water access points and hydration pathways in CLC H+/Cl- transporters. Proc Natl Acad Sci U S A. 2014;111(5):1819-24. PubMed Central PMCID: PMC3918786. (Bridge 3, Bridge 5, CMC)
  27. A. Das, M. Gur, M. H. Cheng, S. Jo, I. Bahar and B. Roux. Exploring the conformational transitions of biomolecular systems using a simple two-state anisotropic network model. PLoS Comput Biol. 2014;10(4):e1003521. PubMed Central PMCID: PMC3974643. (CMC)
  28. B. Dang, T. Kubota, A. M. Correa, F. Bezanilla and S. B. Kent. Total chemical synthesis of biologically active fluorescent dye-labeled Ts1 toxin. Angew Chem Int Ed Engl. 2014;53(34):8970-4. (PCC)
  29. A. E. Blanchard, M. J. Arcario, K. Schulten and E. Tajkhorshid. A highly tilted membrane configuration for the prefusion state of synaptobrevin. Biophys J. 2014;107(9):2112-21. PubMed Central PMCID: PMC4223215. (CMC)
  30. L. J. Bailey, K. M. Sheehy, R. J. Hoey, Z. P. Schaefer, M. Ura and A. A. Kossiakoff. Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments. J Immunol Methods. 2014;415:24-30. PubMed Central PMCID: PMC4257880. (sAB)
  31. P. C. Wen, B. Verhalen, S. Wilkens, H. S. McHaourab and E. Tajkhorshid. On the origin of large flexibility of P-glycoprotein in the inward-facing state. J Biol Chem. 2013;288(26):19211-20. PubMed Central PMCID: PMC3696692. (Bridge 2, CMC)
  32. E. A. van der Cruijsen, D. Nand, M. Weingarth, A. Prokofyev, S. Hornig, A. A. Cukkemane, A. M. Bonvin, S. Becker, R. E. Hulse, E. Perozo, O. Pongs and M. Baldus. Importance of lipid-pore loop interface for potassium channel structure and function. Proc Natl Acad Sci U S A. 2013;110(32):13008-13. PubMed Central PMCID: PMC3740848. (Bridge 4)
  33. S. A. Shaikh, J. Li, G. Enkavi, P. C. Wen, Z. Huang and E. Tajkhorshid. Visualizing functional motions of membrane transporters with molecular dynamics simulations. Biochemistry (Current Topic). 2013;52(4):569-87. PubMed Central PMCID: PMC3560430. (CMC)
  34. B. Roux and J. Weare. On the statistical equivalence of restrained-ensemble simulations with the maximum entropy method. J Chem Phys. 2013;138(8):084107. PubMed Central PMCID: PMC3598863. (CMC)
  35. B. Roux and S. M. Islam. Restrained-ensemble molecular dynamics simulations based on distance histograms from double electron-electron resonance spectroscopy. J Phys Chem B. 2013;117(17):4733-9. PubMed Central PMCID: PMC3683991. (CMC)
  36. S. A. Pless, A. P. Niciforovic, J. D. Galpin, J. J. Nunez, H. T. Kurata and C. A. Ahern. A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel. Nat Commun. 2013;4:1784. PubMed Central PMCID: PMC3644096. (PCC)
  37. S. A. Pless, J. D. Galpin, A. P. Niciforovic, H. T. Kurata and C. A. Ahern. Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels. Elife. 2013;2:e01289. PubMed Central PMCID: PMC3852034. (PCC)
  38. M. Paduch, A. Koide, S. Uysal, S. S. Rizk, S. Koide and A. A. Kossiakoff. Generating conformation-specific synthetic antibodies to trap proteins in selected functional states. Methods. 2013;60(1):3-14. PubMed Central PMCID: PMC3650108. (sAB)
  39. M. Moradi and E. Tajkhorshid. Mechanistic picture for conformational transition of a membrane transporter at atomic resolution. Proc Natl Acad Sci U S A. 2013;110(47):18916-21. PubMed Central PMCID: PMC3839739. (Bridge 2, CMC)
  40. S. Mondal, G. Khelashvili, L. Shi and H. Weinstein. The cost of living in the membrane: a case study of hydrophobic mismatch for the multi-segment protein LeuT. Chem Phys Lipids. 2013;169:27-38. PubMed Central PMCID: PMC3631462. (Bridge 3, CMC)
  41. C. G. Mayne, J. Saam, K. Schulten, E. Tajkhorshid and J. C. Gumbart. Rapid parameterization of small molecules using the Force Field Toolkit. J Comput Chem. 2013;34(32):2757-70. PubMed Central PMCID: PMC3874408. (CMC)
  42. M. Lu, J. Symersky, M. Radchenko, A. Koide, Y. Guo, R. Nie and S. Koide. Structures of a Na+-coupled, substrate-bound MATE multidrug transporter. Proc Natl Acad Sci U S A. 2013;110(6):2099-104. PubMed Central PMCID: PMC3568332. (sAB)
  43. G. Khelashvili, M. V. LeVine, L. Shi, M. Quick, J. A. Javitch and H. Weinstein. The membrane protein LeuT in micellar systems: aggregation dynamics and detergent binding to the S2 site. J Am Chem Soc. 2013;135(38):14266-75. PubMed Central PMCID: PMC3788620. (Bridge 3, CMC)
  44. A. K. Kantcheva, M. Quick, L. Shi, A. M. Winther, S. Stolzenberg, H. Weinstein, J. A. Javitch and P. Nissen. Chloride binding site of neurotransmitter sodium symporters. Proc Natl Acad Sci U S A. 2013;110(21):8489-94. PubMed Central PMCID: PMC3666746. (Bridge 3, CMC)
  45. S. Jo, W. Jiang, H. S. Lee, B. Roux and W. Im. CHARMM-GUI Ligand Binder for absolute binding free energy calculations and its application. J Chem Inf Model. 2013;53(1):267-77. PubMed Central PMCID: PMC3557591. (CMC)
  46. S. M. Islam, R. A. Stein, H. S. McHaourab and B. Roux. Structural refinement from restrained-ensemble simulations based on EPR/DEER data: application to T4 lysozyme. J Phys Chem B. 2013;117(17):4740-54. PubMed Central PMCID: PMC3684008. (Bridge 2, CMC)
  47. L. Huang and B. Roux. Automated Force Field Parameterization for Non-Polarizable and Polarizable Atomic Models Based on Target Data. J Chem Theory Comput. 2013;9(8). PubMed Central PMCID: PMC3819940. (CMC)
  48. B. Dang, T. Kubota, K. Mandal, F. Bezanilla and S. B. Kent. Native chemical ligation at Asx-Cys, Glx-Cys: chemical synthesis and high-resolution X-ray structure of ShK toxin by racemic protein crystallography. J Am Chem Soc. 2013;135(32):11911-9. PubMed Central PMCID: PMC3838204. (PCC)
  49. A. V. Anzalone, T. Y. Wang, Z. Chen and V. W. Cornish. A common diaryl ether intermediate for the gram-scale synthesis of oxazine and xanthene fluorophores. Angew Chem Int Ed Engl. 2013;52(2):650-4. PubMed Central PMCID: PMC3860831. (PCC)
  50. N. Akyuz, R. B. Altman, S. C. Blanchard and O. Boudker. Transport dynamics in a glutamate transporter homologue. Nature. 2013;502(7469):114-8. PubMed Central PMCID: PMC3829612. (ex-Pilot 3)
  51. C. Zhao, S. Stolzenberg, L. Gracia, H. Weinstein, S. Noskov and L. Shi. Ion-controlled conformational dynamics in the outward-open transition from an occluded state of LeuT. Biophys J. 2012;103(5):878-88. PubMed Central PMCID: PMC3433624. (Bridge 3)
  52. S. Stolzenberg, G. Khelashvili and H. Weinstein. Structural intermediates in a model of the substrate translocation path of the bacterial glutamate transporter homologue GltPh. J Phys Chem B. 2012;116(18):5372-83. PubMed Central PMCID: PMC3350225. (CMC)
  53. M. Quick, L. Shi, B. Zehnpfennig, H. Weinstein and J. A. Javitch. Experimental conditions can obscure the second high-affinity site in LeuT. Nat Struct Mol Biol. 2012;19(2):207-11. PubMed Central PMCID: PMC3272158. (Bridge 3)
  54. Y. Z. Ohkubo, T. V. Pogorelov, M. J. Arcario, G. A. Christensen and E. Tajkhorshid. Accelerating membrane insertion of peripheral proteins with a novel membrane mimetic model. Biophys J. 2012;102(9):2130-9. PubMed Central PMCID: PMC3341550. (CMC)
  55. M. Musgaard, L. Thogersen, B. Schiott and E. Tajkhorshid. Tracing cytoplasmic Ca(2+) ion and water access points in the Ca(2+)-ATPase. Biophys J. 2012;102(2):268-77. PubMed Central PMCID: PMC3260667. (CMC)
  56. J. Li and E. Tajkhorshid. A gate-free pathway for substrate release from the inward-facing state of the Na(+)-galactose transporter. Biochim Biophys Acta. 2012;1818(2):263-71. PubMed Central PMCID: PMC3253917. (Bridge 3, CMC)
  57. T. R. Lezon and I. Bahar. Constraints imposed by the membrane selectively guide the alternating access dynamics of the glutamate transporter GltPh. Biophys J. 2012;102(6):1331-40. PubMed Central PMCID: PMC3309413. (CMC)
  58. S. Koide, A. Koide and D. Lipovsek. Target-binding proteins based on the 10th human fibronectin type III domain ((1)(0)Fn3). Methods Enzymol. 2012;503:135-56. (sAB)
  59. F. Khalili-Araghi, E. Tajkhorshid, B. Roux and K. Schulten. Molecular dynamics investigation of the omega-current in the Kv1.2 voltage sensor domains. Biophys J. 2012;102(2):258-67. PubMed Central PMCID: PMC3260662. (CMC)
  60. H. C. Hyde, W. Sandtner, E. Vargas, A. T. Dagcan, J. L. Robertson, B. Roux, A. M. Correa and F. Bezanilla. Nano-positioning system for structural analysis of functional homomeric proteins in multiple conformations. Structure. 2012;20(10):1629-40. PubMed Central PMCID: PMC3633233. (Bridge 1, CMC)
  61. J. Gumbart and B. Roux. Determination of membrane-insertion free energies by molecular dynamics simulations. Biophys J. 2012;102(4):795-801. PubMed Central PMCID: PMC3283816. (CMC)
  62. J. Gumbart, F. Khalili-Araghi, M. Sotomayor and B. Roux. Constant electric field simulations of the membrane potential illustrated with simple systems. Biochim Biophys Acta. 2012;1818(2):294-302. PubMed Central PMCID: PMC3575077. (CMC)
  63. O. Dalmas, H. C. Hyde, R. E. Hulse and E. Perozo. Symmetry-constrained analysis of pulsed double electron-electron resonance (DEER) spectroscopy reveals the dynamic nature of the KcsA activation gate. J Am Chem Soc. 2012;134(39):16360-9. PubMed Central PMCID: PMC3845908. (Bridge 4)
  64. D. Bhatt and I. Bahar. An adaptive weighted ensemble procedure for efficient computation of free energies and first passage rates. J Chem Phys. 2012;137(10):104101. PubMed Central PMCID: PMC3460967. (CMC)
  65. P. C. Wen and E. Tajkhorshid. Conformational coupling of the nucleotide-binding and the transmembrane domains in ABC transporters. Biophys J. 2011;101(3):680-90. PubMed Central PMCID: PMC3145290. (Bridge 2)
  66. S. Uysal, L. G. Cuello, D. M. Cortes, S. Koide, A. A. Kossiakoff and E. Perozo. Mechanism of activation gating in the full-length KcsA K+ channel. Proc Natl Acad Sci U S A. 2011;108(29):11896-9. PubMed Central PMCID: PMC3141920. (Bridge 4, sAB)
  67. W. Sandtner, B. Egwolf, F. Khalili-Araghi, J. E. Sanchez-Rodriguez, B. Roux, F. Bezanilla and M. Holmgren. Ouabain binding site in a functioning Na+/K+ ATPase. J Biol Chem. 2011;286(44):38177-83. PubMed Central PMCID: PMC3207469. (Bridge 1)
  68. S. Mondal, G. Khelashvili, J. Shan, O. S. Andersen and H. Weinstein. Quantitative modeling of membrane deformations by multihelical membrane proteins: application to G-protein coupled receptors. Biophys J. 2011;101(9):2092-101. PubMed Central PMCID: PMC3207176. (CMC)
  69. H. S. McHaourab, P. R. Steed and K. Kazmier. Toward the fourth dimension of membrane protein structure: insight into dynamics from spin-labeling EPR spectroscopy. Structure. 2011;19(11):1549-61. PubMed Central PMCID: PMC3224804. (Bridge 2)
  70. C. Jing and V. W. Cornish. Chemical tags for labeling proteins inside living cells. Acc Chem Res. 2011;44(9):784-92. PubMed Central PMCID: PMC3232020. (PCC)
  71. J. F. Cordero-Morales, V. Jogini, S. Chakrapani and E. Perozo. A multipoint hydrogen-bond network underlying KcsA C-type inactivation. Biophys J. 2011;100(10):2387-93. PubMed Central PMCID: PMC3093550. (Bridge 4)
  72. S. Chakrapani, J. F. Cordero-Morales, V. Jogini, A. C. Pan, D. M. Cortes, B. Roux and E. Perozo. On the structural basis of modal gating behavior in K(+) channels. Nat Struct Mol Biol. 2011;18(1):67-74. PubMed Central PMCID: PMC3059741. (Bridge 4, CMC)
  73. J. P. Castillo, D. De Giorgis, D. Basilio, D. C. Gadsby, J. J. Rosenthal, R. Latorre, M. Holmgren and F. Bezanilla. Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+/K+-ATPase in the giant axon of the Humboldt squid. Proc Natl Acad Sci U S A. 2011;108(51):20556-61. PubMed Central PMCID: PMC3251152. (Bridge 1)
  74. B. L. Pentelute, K. Mandal, Z. P. Gates, M. R. Sawaya, T. O. Yeates and S. B. Kent. Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography. Chem Commun (Camb). 2010;46(43):8174-6. (PCC)

Publications Associated with the Consortium

These publications are related to the overall mission of the MPSDC projects and cores.

CMC=Computational Modeling Core; PCC=Protein Production and Chemistry Core; SAB=Synthetic Antigen Binder Core, SIC=Spectroscopy and Instrumentation Core (from members of the new Spectroscopy and Instrumentation Core)

  1. Q. Zhou, J. Li, H. Yu, Y. Zhai, Z. Gao, Y. Liu, X. Pang, L. Zhang, K. Schulten, F. Sun and C. Chen. Molecular insights into the membrane-associated phosphatidylinositol 4-kinase IIalpha. Nat Commun. 2014;5:3552. PubMed Central PMCID: PMC3974213. (CMC)
  2. J. V. Vermaas and E. Tajkhorshid. Conformational heterogeneity of alpha-synuclein in membrane. Biochim Biophys Acta. 2014;1838:3107–3117. (CMC)
  3. J. V. Vermaas and E. Tajkhorshid. A microscopic view of phospholipid insertion into biological membranes. J Phys Chem B. 2014;118(7):1754-64. PubMed Central PMCID: PMC3933253. (CMC)
  4. A. K. Shukla, G. H. Westfield, K. Xiao, R. I. Reis, L. Y. Huang, P. Tripathi-Shukla, J. Qian, S. Li, A. Blanc, A. N. Oleskie, A. M. Dosey, M. Su, C. R. Liang, L. L. Gu, J. M. Shan, X. Chen, R. Hanna, M. Choi, X. J. Yao, B. U. Klink, A. W. Kahsai, S. S. Sidhu, S. Koide, P. A. Penczek, A. A. Kossiakoff, V. L. Woods, Jr., B. K. Kobilka, G. Skiniotis and R. J. Lefkowitz. Visualization of arrestin recruitment by a G-protein-coupled receptor. Nature. 2014;512(7513):218-22. PubMed Central PMCID: PMC4134437. (sAB)
  5. T. V. Pogorelov, J. V. Vermaas, M. J. Arcario and E. Tajkhorshid. Partitioning of amino acids into a model membrane: capturing the interface. J Phys Chem B. 2014;118(6):1481-92. PubMed Central PMCID: PMC3983343. (CMC)
  6. S. A. Pless, F. D. Elstone, A. P. Niciforovic, J. D. Galpin, R. Yang, H. T. Kurata and C. A. Ahern. Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains. J Gen Physiol. 2014;143(5):645-56. PubMed Central PMCID: PMC4003186. (PCC)
  7. F. Lohr, A. Laguerre, C. Bock, S. Reckel, P. J. Connolly, N. Abdul-Manan, F. Tumulka, R. Abele, J. M. Moore and V. Dotsch. Time-shared experiments for efficient assignment of triple-selectively labeled proteins. J Magn Reson. 2014;248:81-95. PubMed Central PMCID: PMC4254601. (PCC)
  8. Q. Li, S. Wanderling, P. Sompornpisut and E. Perozo. Structural basis of lipid-driven conformational transitions in the KvAP voltage-sensing domain. Nat Struct Mol Biol. 2014;21(2):160-6. PubMed Central PMCID: PMC3946318. (PCC)
  9. E. J. Koers, E. A. van der Cruijsen, M. Rosay, M. Weingarth, A. Prokofyev, C. Sauvee, O. Ouari, J. van der Zwan, O. Pongs, P. Tordo, W. E. Maas and M. Baldus. NMR-based structural biology enhanced by dynamic nuclear polarization at high magnetic field. J Biomol NMR. 2014;60(2-3):157-68.
  10. N. Johner, S. Mondal, G. Morra, M. Caffrey, H. Weinstein and G. Khelashvili. Protein and lipid interactions driving molecular mechanisms of in meso crystallization. J Am Chem Soc. 2014;136(8):3271-84. PubMed Central PMCID: PMC3985912. (CMC)
  11. H. Huang, E. J. Levin, S. Liu, Y. Bai, S. W. Lockless and M. Zhou. Structure of a membrane-embedded prenyltransferase homologous to UBIAD1. PLoS Biol. 2014;12(7):e1001911. PubMed Central PMCID: PMC4106721.
  12. P. J. Hamilton, A. N. Belovich, G. Khelashvili, C. Saunders, K. Erreger, J. A. Javitch, H. H. Sitte, H. Weinstein, H. J. Matthies and A. Galli. PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein. Nat Chem Biol. 2014;10(7):582-9. PubMed Central PMCID: PMC4062427. (Bridge 3)
  13. K. L. Durr, L. Chen, R. A. Stein, R. De Zorzi, I. M. Folea, T. Walz, H. S. McHaourab and E. Gouaux. Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States. Cell. 2014;158(4):778-92. PubMed Central PMCID: PMC4263325. (SIC)
  14. Y. Dehnes, J. Shan, T. Beuming, L. Shi, H. Weinstein and J. A. Javitch. Conformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocation. Neurochem Int. 2014;73:4-15. PubMed Central PMCID: PMC4058377. (Bridge 3)
  15. N. S. Alexander, A. M. Preininger, A. I. Kaya, R. A. Stein, H. E. Hamm and J. Meiler. Energetic analysis of the rhodopsin-G-protein complex links the alpha5 helix to GDP release. Nat Struct Mol Biol. 2014;21(1):56-63. PubMed Central PMCID: PMC3947367. (SIC)
  16. B. F. A., A. N. and E. Tajkhorshid. Thermodynamic Insight into Spontaneous Hydration and Rapid Water Permeation in Aquaporins. Appl Phys Lett. 2014;105(8):083702. PubMed Central PMCID: PMC4187254. (CMC)
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