March 3, 2017 • 9:00am – 6:00pm
Saieh Hall, University of Chicago
In the past few years, a revolution in cryo electron microscopy has taken structural biology by storm. The recent integration of new developments in electron microscopes, direct electron detection cameras, and advances in image analysis methods are allowing the expansion of high resolution structural molecular biology in new and exciting directions by direct visualization of macromolecules and their complexes. The next decades will be dominated by the study of protein-protein, protein-nucleic acid complexes, molecular machines, and their conformational changes in ways that were impossible before due to their size and/or the need to study them in crystalline form. In addition, developments in many aspects of electron microscopy are providing new tools for the study of biological molecules from the single molecule to the cellular level. The Third Coast Workshop on Biological Cryo-EM will address key developments in this fast advancing field and will provide scientists from different disciplines with an opportunity to discuss the state of the field and exchange views from both experimental and computational perspectives.
We are pleased to invite you to the first edition of the NAMD developer workshop jointly organized by the University of Illinois, Urbana-Champaign and the University of Chicago, and to be held on the campus of the University of Chicago.
This workshop is intended to gather the community of NAMD developers for fruitful exchange on current and future developments of the program. It will consist of short presentations aimed at covering practical coding aspects, ongoing developments, architecture specificities, implementations of novel algorithms, as well as broader topics, notably future directions of the program and the parallel programming environment charm++ it uses.
This workshop is not intended for scientific presentations about applications, although illustrative applications of on-going code developments would be welcome.
The workshop will be held at the Gordon Center for Integrative Science on the University of Chicago campus and is sponsored by:
National Institute of General Medical Sciences
NIH Center for Macromolecular Modeling and Bioinformatics (NIH 9P41GM104601)
NIH Hands-on Workshops on Computational Biophysics (NIH 1R25GM103771-01)
The Membrane Protein Structural Dynamics Consortium (NIH grant NIGMS U54-GM087519)
For more information and registration, visit this page.
Francisco Bezanilla, Past President presenting an award to Robert Nakamoto.(Click to enlarge)
The Membrane Protein Structural Dynamics Consortium is always very well represented at the annual Biophysical Society meeting, as can be seen by Klaus Schulten‘s National Lecture in 2015 as well as at the level of participants in a remarkably large number of workshops, symposia, and presentations. This is also reflected in Consortium members being actively involved at the leadership level, including Francisco Bezanilla‘s tenure as Biophysical Society President from 2012 to 2014 and Robert Nakamoto and Olga Boudker‘s service in the current Biophysical Society leadership council.
On August 31, 2015 the Biophysical Society announced that MPSDC Chair Eduardo Perozo was elected as a 2016 Society Fellow. This award honors the Society’s distinguished members who have demonstrated excellence in science, contributed to the expansion of the field of biophysics, and supported the Biophysical Society. The Fellows will be honored at the Awards Ceremony during the Biophysical Society’s 60th Annual Meeting on Monday February 29, 2016 at the Los Angeles Convention Center in Los Angeles, California. Perozo was elected for his leadership and fundamental contributions in ion channel biophysics.
At next year’s meeting in Los Angeles, MPSDC members will participate in a number of specialty symposia and workshops organized by the Biophysical society (more information on the nature of these symposia and workshops can be found on the Biophysical Society meeting website here). We would like to highlight the following in particular (though there are and will certainly be more ways in which Consortium members are involved with the meeting):
- Francisco Bezanilla (University of Chicago) is participating in a symposium on Voltage Sensing and Gating.
- Olga Boudker (Weill Cornell Medical College) is receiving the Michael and Kate Bárány Award during the meeting’s award symposium. During this session, award recipients are recognized and each give a short talk about the work for which they are being recognized. Congratulations, Olga!
- Yifan Cheng (University of California, San Francisco) is co-chairing the Cryo-EM Subgroup 2016 Symposium
- Claudio Grosman(UIUC) is participating in a symposium on Pentameric Ligand-gated Ion Channels: New Insights from Structure and Function.
- Benoît Roux (University of Chicago) is participating in a workshop about Computational Methods for Ion Permeation and Selectivity
- Emad Tajkhorshid (UIUC) will once again be chairing the Permeation & Transport Subgroup 2015 Symposium. He chaired the same subgroup last year.
Last year, MPSDC member and one of our keynote speakers at Frontiers in Membrane Protein Structural Dynamics 2014 Klaus Schulten (UIUC) gave the prestigious National Lecture. The National Lecturer is the highest award given each year by the Biophysical Society. Dr. Schulten’s 2015 National Lecture lecture can be viewed in full here.
See also: interviews from the 59th Biophysical Society Meeting with 2015 National Lecturer Klaus Schulten and Harel Weinstein.
See also: interviews from the 58th Biophysical Society Meeting with Francisco Bezanilla, Past President and Robert Nakamoto, Chair of the 2014 BPS Program Committee.
Structural biology of membrane proteins, particularly from higher eukaryotes, has been transformed in the last two years. New and improved technologies such as electron microscopy and free electron lasers have led to the rapid increase in the number of structures solved and the complexity of these structures. This symposium will highlight advances in technology, celebrate the unprecedented advances in understanding of membrane protein structure and function, and look to the future for this rapidly developing field.
Frontiers in Integral Membrane Protein Structural Biology 2015 is set to take place in Oxford, United Kingdom from October 5th until the 7th.
MPSDC Chair Eduardo Perozo will participate with a lecture titled “Asymmetric Conformational Transition Underlies Mg2+-Driven Gating in CorA.”
Former MPSDC-sponsored Frontiers in Membrane Protein Structural Dynamics conference speakers Robert Stroud (who gave of the two 2014 keynote lectures) and Robert Tampé are also participating.
Learn more about the symposium »
Membrane Proteins: Structure and Function is a conference featuring eight oral sessions and one poster session covering the latest findings across many topics in membrane proteins. It is set to take place on May 11-15, 2015 in Suzhou, China.
The conference was co-organized by MPSDC members Robert Nakamoto (University of Virginia) and Ming Zhou (Baylor College of Medicine). In addition, the following Consortium members are presenting at the conference:
- Volker Dötsch, Goethe Universität Frankfurt
Abstract title:Structure determination of membrane proteins by NMR spectroscopy based on selective labelling approaches and cell-free protein synthesis
- Eduardo Perozo, The University of Chicago
Abstract title:The Structural Basis of Charge Translocation in Voltage Sensing Domains
- Emad Tajkhorshid, University Illinois at Urbana-Champaign
Abstract title:Characterizing Large-scale Conformational Changes in Membrane Transporters at High Spatial and Temporal Resolutions with Advanced Computational Methods
- Francis Valiyaveetil, Oregon Health & Science University
Abstract title:Probing Functional Mechanisms in Ion Channels and Transporters using Unnatural Mutagenesis.
- Ming Zhou, Baylor College of Medicine
Abstract title:Structure of a Mammalian Stearoyl-CoA Desaturase