The 56th Annual Biophysical Society Meeting is fast approaching, and this year members of the Membrane Protein Structural Dynamics Consortium (MPSDC) have collaborated on no less than 72 presentations and posters taking place in various subgroups, platforms, symposia, mini-symposia, and workshops.
Additionally, Klaus Schulten will be honored at the Meeting’s Awards Ceremony as a 2012 Society Fellow during the Biophysical Society’s on Monday February 27, 2012 for his groundbreaking effort to develop computational molecular biology as an important tool to solve problems in biophysics. Francisco Bezanilla was voted President-Elect during the 2011 Society meetings and will begin officially holding this office at the Meeting. His term as President will begin at the 2013 Annual Meeting in Philadelphia, Pennsylvania. Finally, Merritt Maduke will begin her three-year term as a Councilor of the Biophysical Society as well.
The table after the jump provides a complete itinerary of all Consortium-affiliated presentations and posters. We would like to feature especially those 12 in which two or more Consortium members or associate members have collaborated (highlighted in light blue). The table is ordered by date and time.
Download a pdf of this itinerary including abstracts »
Authors & Institutions |
Abstract Title & Session |
Information |
| Benoit Roux. BMB, University of Chicago, Chicago, IL, USA. | MOLECULAR DYNAMICS COMPUTATIONS OF STANDARD BINDING FREE ENERGIES
015.Subgroup: Molecular Biophysics |
Presentation (15-Subg) Sat 2/25, 9:00 AM -10:00 AM Room 29ABC |
| Eduardo Perozo. Dept of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA. | A MOLECULAR MECHANISM OF ACTIVATION-DEACTIVATION GATING IN THE MG2+-DEPENDENT MG2+ CHANNEL CORA
026.Subgroup: Permeation & Transport |
Presentation (26-Subg) Sat 2/25, 1:30 PM – 1:30 PM Room 28AB |
| Emad Tajkhorshid. Department of Biochemistry, and Beckman Institute, University of Illinois at Urbana Champaign, Urbana, IL, USA. | ACCELERATING MEMBRANE INSERTION OF PERIPHERAL PROTEINS WITH A NOVEL MEMBRANE MIMETIC MODEL
023.Subgroup: Membrane Structure & Assembly |
Presentation (33-Subg) Sat 2/25, 1:00 PM – 1:35 PM Ballroom 20A |
| Katarina Ruscic, Francesco Miceli, Carlos Villalba-Galea, Francisco Bezanilla, Steve Goldstein. University of Chicago, Chicago, IL, USA, Brandeis University, Waltham, MA, USA, IRCCS Bambino Gesù Children’s Hospital, Rome, Italy, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. | KCNE1 SLOWS THE VOLTAGE SENSORS OF KCNQ1
042.Platform: Voltage-gated K Channels: Gating |
Presentation (71-Plat) Sun 2/26, 8:15 AM – 10:00 AM Room 25ABC |
| Chaitanya Sathe, Xueqing Zou, Jean-Pierre Leburton, Klaus Schulten. UIUC, Urbana, IL, USA. | COMPUTATIONAL INVESTIGATION OF GRAPHENE NANO PORE DNA DETECTION
091.36.Micro & Nanotechnology: Nanopores I |
Poster (1028-Pos, #B814) Sun 2/26, 1:45 PM – 3:45 PM Hall FGH |
| Boon Chong Goh, Xueqing Zou, Michael J. Rynkiewicz, Barbara A. Seaton, Klaus Schulten. University of Illinois at Urbana-Champaign, Urbana, IL, USA, Beckman Institute, Urbana, IL, USA, Boston University, Boston, MA, USA. | MECHANISM OF INTERACTION BETWEEN LUNG SURFACTANT PROTEIN-D AND INFLUENZA A VIRUS HEMAGGLUTININ
091.05.Protein-Ligand Interactions I |
Poster (318-Pos, #B104) Sun 2/26, 1:45 PM – 3:45 PM Hall FGH |
| Angelica M. Lopez-Rodriguez, Miguel Holmgren. NIH, Bethesda, MD, USA. | RESCUING PROPER TRAFFICKING OF CYSTEINE MUTANT PROTEINS
091.20.Cyclic Nucleotide-gated Channels |
Poster (654-Pos, #B440) Sun 2/26, 1:45 PM – 3:45 PM Hall FGH |
| David Papke, Claudio Grosman. University of Illinois, Urbana-Champaign, Urbana, IL, USA. | EXAMINING THE ROLE OF THE M1-M2 LOOP IN CYS-LOOP RECEPTOR DESENSITIZATION AND GATING
091.16.Ligand-gated Channels I |
Poster (570-Pos, #B356) Sun 2/26, 1:45 PM – 3:45 PM Hall FGH |
| Qufei Li, Sherry Wanderling, Carlos A. Villalba-Galea, Eduardo Perozo. Institute for Biophysical Dynamics and Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA, Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. | THE RESTING AND ACTIVATED CONFORMATIONS OF THE VOLTAGE SENSOR OF CI-VSP FROM FUNCTIONAL AND SOLVENT ACCESSIBILITY DETERMINATIONS
081.Platform: Voltage-sensitive Proteins |
Presentation (179-Plat) Sun 2/26, 4:00 PM – 4:15 PM Room 29ABC |
| Martin L. Prieto, Omer Oralkan, Butrus T. Khuri-Yakub, Merritt Maduke. Stanford University, Stanford, CA, USA. | ULTRASOUND-INDUCED CURRENTS IN PLANAR LIPID BLAYERS: ORIGINS AND POTENTIAL PHYSIOLOGICAL SIGNIFICANCE
079.Platform: Membrane Dynamics & Bilayer Probes |
Presentation (169-Plat) Sun 2/26, 5:30 PM – 5:45 PM Room 24ABC |
| Lewis Kay. Medical Genetics & Microbiology, University of Toronto, Toronto, ON, Canada. | SEEING THE INVISIBLE BY SOLUTION NMR
090.Workshop: Measuring Excursions from the “Structure” (X-Ray Crystallography, NMR, Simulations) |
Presentation (211-Wkshp) Sun 2/26, 7:30 PM Ballroom 20BC |
| Wei Han, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | TRANSIENT WATER CHAINS CONNECTING THE CYTOPLASMIC AND EXTRACELLULAR GLUTAMATE GATES IN CLC
101.Platform: Membrane Transporters & Exchangers I |
Presentation (1083-Plat) Mon 2/27, 8:30 AM – 8:45 AM Room 24ABC |
| Elena J. Levin, Yu Cao, Giray Enkavi, Matthias Quick, Yaping Pan, Emad Tajkhorshid, Ming Zhou. Columbia University, New York, NY, USA, University of Illinois at Urbana-Champaign, Urbana, IL, USA. | MECHANISM AND REGULATION OF UREA PERMEATION IN A MAMMALIAN UREA CHANNEL
101.Platform: Membrane Transporters & Exchangers I |
Presentation (1089-Plat) Mon 2/27, 10:00AM – 10:15 AM Room ABC |
| Melih Sener, Johan Strumpfer, Klaus Schulten. UIUC, Urbana, IL, USA. | ATOMIC LEVEL SUPRAMOLECULAR ORGANIZATION AND FUNCTION OF AN ENTIRE BIOENERGETIC ORGANELLE
144.04.Protein Assemblies |
Poster (1314-Pos, #B84) Mon 2/27, 1:45 PM – 3:45 PM Hall FGH |
| Y Zenmei Ohkubo, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | FORMATION OF TERNARY COMPLEX OF FACTOR VIIA, TISSUE FACTOR, AND FACTOR X ON THE SURFACE OF ANIONIC MEMBRANE
144.04.Protein Assemblies |
Poster (1316-Pos, #B86) Mon 2/27, 1:45 PM – 3:45 PM Hall FGH |
| Christopher N. Rowley, Benoit Roux. University of Chicago, Chicago, IL, USA. | INTERPRETING THE BARIUM BLOCKADES OF POTASSIUM CHANNELS WITH THE MULTI-ION PERMEATION FREE ENERGY SURFACE
144.23.Biophysics of Ion Permeation |
Poster (1692-Pos, #B462) Mon 2/27, 1:45 PM – 3:45 PM Hall FGH |
| Tomoya Kubota, Jérôme J. Lacroix, Francisco Bezanilla, Ana M. Correa. The University of Chicago, Chicago, IL, USA. | PROBING S4 LENGTH CHANGES DURING GATING WITH LRET
144.05.Membrane Protein Structure I |
Poster (1343-Pos, #B113) Mon 2/27, 1:45 PM – 3:45 PM Hall FGH |
| Johan A. Strumpfer, Eleonore von Castelmur, Barbara Franke, Sonia Barbieri, Julijus Bogomolovas, Hiroshi Qadota, Petr Konarv, Dmitri Svergun, Siegfried Labeit, Klaus Schulten, Guy M. Benian, Olga Mayans. University of Illinois at Urbana Champaign, Urbana, IL, USA, Beckman Institute, Urbana, IL, USA, Institute of Integrative Biology, University of Liverpool, Liverpool, IL, USA, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom, Universitätsmedizin Mannheim, Mannheim, Germany, Department of Pathology, Emory University, Atlanta, GA, USA, European Molecular Biology Laboratory, Hamburg, Germany, Department for Integrative Pathophysiology, Universitätsmedizin Mannheim, Mannheim, Germany. | STRETCHING OF TWITCHIN KINASE
144.29.Muscle: Fiber & Molecular Mechanics & Structure II |
Poster (1832-Pos, #B602) Mon 2/27, 1:45 PM – 3:45 PM Hall FGH |
| Tao Jiang, Maria Spies, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | CHARACTERIZING AN INTERMEDIATE STATE BETWEEN INACTIVE AND ACTIVE STATES OF RECA
144.10.DNA Replication, Recombination, and Repair |
Poster (1439-Pos, #B209) Mon 2/27, 1:45 PM – 3:45 PM Hall FGH |
| Olivier Dalmas, H. Clark Hyde, Eduardo Perozo. The University of Chicago, Chicago, IL, USA. | DISTANCE DETERMINATION IN MULTIMERIC MEMBRANE PROTEIN BY SYMMETRY CONSTRAINED ANALYSIS OF DOUBLE ELECTRON-ELECTRON RESONANCE SPECTROSCOPY.
144.41.EPR Spectroscopy |
Poster (2059-Pos, #B829) Mon 2/27, 1:45 PM – 3:45 PM Hall FGH |
| Pornthep Sompornpisut, Olivier Dalmas, Eduardo Perozo. Chulalongkorn University, Bangkok, Thailand, The University of Chicago, Chicago, IL, USA. | THE OPEN CONFORMATION OF THE MG2+ CHANNEL CORA FROM SOLVENT ACCESSIBILITY AND DISTANCE CONSTRAINTS
144.24.Ligand-gated Channels II |
Poster (1717-Pos, #B487) Mon 2/27, 1:45 PM – 3:45 PM Hall FGH |
| Mark J. Arcario, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Champaign, IL, USA. | CAPTURING SPONTANEOUS MEMBRANE INSERTION AND MEMBRANE-INDUCED CONFORMATIONAL CHANGES OF TALIN AT AN ATOMIC RESOLUTION
144.15.Lipids & Signaling on Membrane Surfaces |
Poster (1540-Pos, #B310) Mon 2/27, 1:45 PM – 3:45 PM Hall FGH |
| Hang Yu, Klaus Schulten, Ying Yin, Anton Arkhipov. University of Illinois, Urbana Champaign, Urbana, IL, USA. | COMPUTER SIMULATION OF MEMBRANE TUBULATION BY EFC F-BAR DOMAIN LATTICES
134.Platform: Interfacial Protein-Lipid Interactions I |
Presentation (1195-Plat) Mon 2/27, 5:15 PM – 5:30 PM Room 24ABC |
| Merritt Maduke. Stanford University, Stanford, CA, USA. | CLC TRANSPORTERS: THE SEARCH FOR CONFORMATIONAL CHANGE
152.Symposium: Transporter-Channel Interface |
Presentation (2071-Symp) Tue 2/28, 8:45 AM – 9:15 AM Ballroom 20D |
| Taras V. Pogorelov, Emad Tajkhorshid. University of Illinois, Urbana, IL, USA. | GLYCOPHORIN A HELIX INSERTION, POSITIONING, AND DIMERIZATION IN MODEL MEMBRANES
156.Platform: Membrane Structure II |
Presentation (2101-Plat) Tue 2/28, 9:15 AM – 9:30 AM Room 29ABC |
| Leigh D. Plant, Leandro Zuniga, Dan Araki, Jeremy D. Marks, Steve Goldstein. Brandeis University, Waltham, MA, USA, University of Chicago, Chicago, IL, USA. | K2P1 ASSEMBLES WITH K2P3 OR K2P9 TO FORM SUMO-REGULATED TASK BACKGROUND CHANNELS IN CEREBELLAR GRANULE NEURONS.
155.Platform: Channel Regulation & Modulation |
Presentation (2094-Plat) Tue 2/28, 9:30 AM – 9:45 AM Room 25ABC |
| Gisela D. Cymes, Claudio Grosman. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | THE RING OF GLUTAMATES IN THE CHARGE-SELECTIVITY FILTER REGION OF THE NICOTINIC RECEPTOR FORMS A SYSTEM OF UNANTICIPATED COMPLEXITY
164.Minisymposium: Ligand-gated Channels |
Presentation (2123-MiniSymp) Tue 2/28, 11:25 AM – 11:45 AM Room 24ABC |
| Jerome J. Lacroix, Stephan A. Pless, Fabiana V. Campos, Luca Maragliano, Jason D. Galpin, Christopher Ahern, Benoit Roux, Francisco Bezanilla. University of Chicago, Chicago, IL, USA, University of British Columbia, Vancouver, BC, Canada, University of Heidelberg, Heidelberg, Germany. | POSITION OF THE SECOND GATING CHARGE ALONG S4 IN AN INTERMEDIATE CONFORMATION OF A K+ CHANNEL VOLTAGE SENSOR
191.20.Voltage-gated K Channels: Gating II |
Poster (2702-Pos, #B472) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Javier L. Baylon, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | CAPTURING INSERTION AND DYNAMICS OF MEMBRANE-BOUND CYTOCHROME P450 3A4 USING A NOVEL MEMBRANE MIMETIC MODEL
191.06.Heme Proteins |
Poster (2374-Pos, #B144) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Christopher G. Mayne, John A. Katzenellenbogen, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | CHARACTERIZING STRUCTURAL AND DYNAMICAL IMPACTS OF AGONIST- AND ANTSGONIST-STABILIZED MUTANTS OF THE ESTROGEN RECEPTOR
191.04.Protein Folding & Stability II |
Poster (2327-Pos, #B97) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Michael F. Priest, Jérôme J. Lacroix, Carlos A. Villalba-Galea, Francisco Bezanilla. University of Chicago, Chicago, IL, USA, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. | REDUCING S3-S4 LINKER LENGTH IN SHAKER K+ CHANNELS STABILIZES THE RELAXED STATE
191.20.Voltage-gated K Channels: Gating II |
Poster (2700-Pos, #B470) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Ricky C.K. Cheng, Shelley M. Elvington, Merritt Maduke. Stanford University, Stanford, CA, USA. | MONITORING SUBSTRATE-DRIVEN CONFORMATIONAL CHANGES OF CLC-EC1 BY [METHYL-13C] METHIONINE NMR
191.17.Membrane Transporters & Exchangers I |
Poster (2653-Pos, #B423) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Thomas A. Chew, Sherwin J. Abraham, Shelley M. Elvington, Merritt Maduke. University of California, San Diego, La Jolla, CA, USA, Stanford University, Stanford, CA, USA. | STRUCTURAL INVESTIGATIONS OF CLC-EC1, A LARGE INTEGRAL MEMBRANE PROTEIN, USING SOLUTION-STATE NMR AND NANODISC TECHNOLOGY
191.17.Membrane Transporters & Exchangers I |
Poster (2652-Pos, #B422) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Sayan Mondal, George Khelashvili, Jennifer Khangulova (Johnston), Hao Wang, Davide Provasi, Olaf S. Andersen, Marta Filizola, Harel Weinstein. Weill Medical College of Cornell University, New York, NY, USA, Mount Sinai School of Medicine, New York, NY, USA. | INTERACTION WITH THE MEMBRANE UNCOVERS ESSENTIAL DIFFERENCES BETWEEN HIGHLY HOMOLOGOUS GPCRS
191.16.Membrane Receptors & Signal Transduction I |
Poster (2621-Pos, #B391) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Mert Gur, Jeffry Madura, Ivet Bahar. Department of Computational & Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA, Department of Chemistry and Biochemistry, Duquesne University, Pittsburgh, PA, USA. | TRANSITION PATHWAYS OF PROTEINS EXPLORED BY COMBINING MOLECULAR DYNAMICS SIMULATIONS AND MONTE CARLO SAMPLING OF COLLECTIVE MODES
191.03.Protein Dynamics II |
Poster (2287-Pos, #B57) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Amelia M. Randich, Eduardo Perozo. University of Chicago, Chicago, IL, USA. | A RANDOM MUTAGENESIS APPROACH TO PROBING ELECTROMECHANICAL COUPLING IN THE HYPERPOLARIZATION-ACTIVATED CHANNEL MVP
191.20.Voltage-gated K Channels: Gating II |
Poster (2695-Pos, #B465) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Luis Cuello, Doris M. Cortes, Eduardo Perozo. Texas Tech University Health Science Center, Lubbock, TX, USA, The University of Chicago, Chicago, IL, USA. | ROLE OF STRUCTURAL WATER IN THE STABILIZATION OF THE KCSA C-TYPE INACTIVATED SELECTIVITY FILTER: EVIDENCE FROM HIGH-RESOLUTION STRUCTURES
191.20.Voltage-gated K Channels: Gating II |
Poster (2694-Pos, #B464) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Wenxun Gan, Mahmoud Moradi, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | CHARACTERIZING TRANSITION PATHWAYS IN THE TRANSPORT CYCLE OF ABC TRANSPORTER MSBA
191.02.Protein Conformation II |
Poster (2267-Pos, #B37) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Joshua V. Vermaas, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | CONFORMATIONAL DYNAMICS OF MEMBRANE-BOUND α-SYNUCLEIN IN A HIGHLY MOBILE MEMBRANE MIMETIC
191.12.Interfacial Protein-Lipid Interactions II |
Poster (2511-Pos, #B281) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Sebastian Stolzenberg, George Khelashvili, Harel Weinstein. Weill Cornell Medical College, Cornell University, New York, NY, USA. | STRUCTURAL INTERMEDIATES IN A MODEL OF THE SUBSTRATE TRANSLOCATION PATH IN THE BACTERIAL GLUTAMATE TRANSPORTER HOMOLOGUE GltPh
191.17.Membrane Transporters & Exchangers I |
Poster (2645-Pos, #B415) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Kimberly I. Matulef, Andrew Howery, R. Lea Sanford, Sabrina Phillips, Sierra Simpson, Sherwin Abraham, Julian Whitelegge, Justin Du Bois, Olaf S. Andersen, Merritt Maduke. University of San Diego, San Diego, CA, USA, Stanford University, Stanford, CA, USA, Cornell University, New York, NY, USA, UCLA, Los Angeles, CA, USA. | CHARACTERIZATION OF A NOVEL CLC-EC1 INHIBITOR
191.17.Membrane Transporters & Exchangers I |
Poster (2651-Pos, #B421) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Yanxin Liu, Johan Strumpfer, Peter L. Freddolino, Martin Gruebele, Klaus Schulten. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | FOLDING THERMODYNAMICS AND KINETICS OF LAMBDA-REPRESSOR FROM ALL-ATOM MOLECULAR DYNAMICS SIMULATIONS
191.04.Protein Folding & Stability II |
Poster (2325-Pos, #B95) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| George Khelashvili, Sayan Mondal, Martin Caffrey, Harel Weinstein. Weill Cornell Medical College, Cornell University, New York, NY, USA, Membrane Structural and Functional Biology Group, Schools of Medicine and Biochemistry & Immunology, Trinity College, Dublin, Ireland. | QUANTITATIVE COMPARISON OF GPCR INTERACTIONS WITH THE LIPID BILAYER OF THE CUBIC AND LAMELLAR MESOPHASES
191.07.Membrane Protein Structure II |
Poster (2381-Pos, #B151) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| Homer Clark Hyde, Jeremy Treger, Francisco Bezanilla. The University of Chicago, Chicago, IL, USA. | VOLTAGE-CLAMPED SUPPORTED BILAYER SYSTEM TO RECORD ION CHANNEL ACTIVITY
191.20.Voltage-gated K Channels: Gating II |
Poster (2701-Pos, #B471) Tue 2/28, 1:45 PM – 3:45 PM Hall FGH |
| George Khelashvili, Aurelio Galli, Harel Weinstein. Weill Cornell Medical College, Cornell University, New York, NY, USA, Vanderbilt University School of Medicine, Nashville, TN, USA. | HOW PIP2 LIPIDS REGULATE THE POSITION AND PHOSPHORYLATION OF THE SYNTAXIN N-TERMINUS
184.Platform: Interfacial Protein-Lipid Interactions II |
Presentation (2200-Plat) Tue 2/28, 4:15 PM – 4:30 PM Room 29ABC |
| James C. Gumbart, Benoit Roux, Klaus Schulten. Argonne National Lab, Argonne, IL, USA, University of Chicago, Chicago, IL, USA, University of Illinois, Urbana-Champaign, Urbana, IL, USA. | SPONTANEOUS MOVEMENT OF TRANSMEMBRANE SEGMENTS FROM SECY INTO THE MEMBRANE
182.Platform: Membrane Protein Function |
Presentation (2188-Plat) Tue 2/28, 5:15 PM – 5:30 PM Room 24ABC |
| Mahmoud Moradi, Giray Enkavi, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | CONFORMATIONAL TRANSITION PATHWAY OF GlpT TRANSPORTER, CHARACTERIZED BY NONEQUILIBRIUM MOLECULAR DYNAMICS SIMULATIONS
200.Platform: Membrane Transporters & Exchangers II |
Presentation (3079-Plat) Wed 2/29, 8:30AM – 8:45 AM Room 30ABC |
| Kelli Kazmier, Matthias Quick, Lei Shi, Harel Weinstein, Jonathan Javitch, Hassane Mchaourab. Vanderbilt University, Nashville, TN, USA, Columbia University College of Physicians and Surgeons, New York, NY, USA, Weill Medical College of Cornell University, New York, NY, USA. | STRUCTURE, DYNAMICS, AND MECHANISM OF THE LEUCINE TRANSPORTER STUDIED BY DOUBLE ELECTRON ELECTRON RESONANCE SPECTROSCOPY
200.Platform: Membrane Transporters & Exchangers II |
Presentation (3081-Plat) Wed 2/29, 9:00 AM – 9:15 AM Room 30ABC |
| Shruti Sharma, Richard A. Stein, Matthias Quick, Sebastian Stolzenberg, Lei Shi, Harel Weinstein, Jonathan Javitch, Hassane Mchaourab. Vanderbilt University, Nashville, TN, USA, Center for Molecular Recognition, Columbia University, New York, NY, USA, Weill Cornell Medical College, New York, NY, USA. | CONFORMATIONAL DYNAMICS IN THE TRANSPORT CYCLE OF LEUCINE TRANSPORTER ON THE EXTRACELLULAR-SIDE
200.Platform: Membrane Transporters & Exchangers II |
Presentation (3082-Plat) Wed 2/29, 9:15 AM – 9:30 AM Room 30ABC |
| Aaron Hoskins, Larry Friedman, Ivan Correa, Ming-Qun Xu, Virginia Cornish, Jeff Gelles, Melissa J. Moore. U. Wisconsin-Madison, Madison, WI, USA, Brandeis University, Waltham, MA, USA, New England Biolabs, Ipswich, MA, USA, Columbia University, New York City, NY, USA, U. Massachusetts Medical School/HHMI, Worcester, MA, USA. | TURNING ON THE SPLICEOSOME
197.Platform: Protein-Nucleic Acid Interactions |
Presentation (3059-Plat) Wed 2/29, 9:30 AM – 9:45 AM Room 24ABC |
| Walter Sandtner, Bernhard Egwolf, Fatemeh Khalili-Araghi, Jorge E. Sanchez-Rodríguez, Benoit Roux, Francisco Bezanilla, Miguel Holmgren. Medical University of Vienna, Vienna, Austria, Max Planck Institute for Biophysical Chemistry, Goettingen, Germany, University of Chicago, Chicago, IL, USA, National Institutes of Health, Bethesda, MD, USA. | OUABAIN BINDING SITE IN A FUNCTIONING NA+/K+-ATPASE
200.Platform: Membrane Transporters & Exchangers II |
Presentation (3084-Plat) Wed 2/29, 9:45 AM – 10:00 AM Room 30ABC |
| Jing Li, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | MECHANISM OF ION COUPLED STATE TRANSITION IN LEUT-FOLD TRANSPORTERS
210.13.Membrane Transporters & Exchangers II |
Poster (3362-Pos, #B223) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Po-Chao Wen, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | FUNDAMENTAL DIFFERENCE OF TRANSPORT MECHANISMS BETWEEN ABC IMPORTERS AND EXPORTERS
210.13.Membrane Transporters & Exchangers II |
Poster (3349-Pos, #B210) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Miguel Holmgren, David C. Gadsby, Francisco Bezanilla, Robert F. Rakowski, Paul De Weer. NIH, Bethesda, MD, USA, Marine Biological Laboratory, Woods Hole, MA, USA. | NA+ ACCESS KINETICS IN THE NA+/K+-ATPASE PUMP
210.24.Ion Motive ATPases |
Poster (3590-Pos, #B451) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Natalie C. Negrey, Robert Nakamoto. University of Virginia, Charlottesville, VA, USA. | INTERACTIONS BETWEEN THE γ SUBUNIT AND THE ε SUBUNIT MEDIATE INHIBITION AND COUPLING IN ESCHERICHIA COLI F1-ATPASE
210.24. Ion Motive ATPases |
Poster (3604-Pos, #B465) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Paween Mahinthichaichan, James Hemp, Robert B. Gennis, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | PROBING GAS DIFFUSION PATHWAYS IN CYTOCHROME C OXIDASE WITH EXPLICIT AND IMPLICIT LIGAND SAMPLINGS
210.25.Membrane Transport |
Poster (3615-Pos, #B476) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Ernesto Vargas, Francisco Bezanilla. University of Chicago, Chicago, IL, USA. | OBSERVING THE ROTATION OF A VOLTAGE-SENSING DOMAIN IN AN ION CHANNEL USING SPECTROSCOPIC METHODS
202.1.Late Poster Presentations |
Poster (L173-Pos, #LB173) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Jorge E. Sanchez-Rodriguez, Fatemeh Khalili-Araghi, Benoit Roux, Miguel Holmgren, Francisco Bezanilla. Department of Biochemistry and Molecular Biology, The University of Chicago, Gordon Center for Integrative Science, Chicago, IL, USA, Molecular Neurophysiology Section, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA. | CHANGES OF INTRAMOLECULAR DISTANCES IN THE Na+/K+ ATPase UPON OUABAIN BINDING
210.24.Ion Motive ATPases |
Poster (3589-Pos, #B450) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Yaroslav D. Bodnar, Klaus Schulten. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | MOLECULAR DYNAMICS FLEXIBLE FITTING OF POLIOVIRUS STRUCTURAL TRANSITIONS DURING INITIATION OF INFECTION AT ATOMIC RESOLUTION
210.06.Virus Structure & Assembly |
Poster (3523-Pos, #B114) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Ping Zou, Hassane Mchaourab. Vanderbilt University, Nashville, TN, USA. | STRUCTURE AND DYNAMICS OF THE MFS MULTIDRUG TRANSPORTER EMRD 210.13.Membrane Transporters & Exchangers II |
Poster (3351-Pos, #B212) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Mizuki Sekiya, Robert Nakamoto, Mayumi Nakanishi-Matsui, Masamitsu Futai. Iwate Medical University, Yahaba, Japan, University of Virginia, Charlottesville, VA, USA. | THE PHYTOPOLYPHENOL PICEATANNOL INHIBITS THE RATE LIMITING STEP OF ROTATIONAL CATALYSIS OF THE F1-ATPASE
210.24.Ion Motive ATPases |
Poster (3605-Pos, #B446) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Pablo Miranda, Jorge E. Contreras, Diana Wesch, Fred J. Sigworth, Miguel Holmgren, Teresa Giraldez. Research Division, University Hospital NS Candelaria, Tenerife, Spain, Department of Physiology, University of La Laguna, Tenerife, Spain, University of Medicine and Dentistry of New Jersey (UMDNJ), Newark, NJ, USA, Department of Cellular and Molecular Physiology Yale University School of Medicine, New Haven, CT, USA, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA. | STATE-DEPENDENT FRET REPORTS LARGE GATING-RING MOTIONS IN BK CHANNELS
210.20.Ca-activated Channels |
Poster (3485-Pos, #B346) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Juan P. Castillo, Daniela De Giorgis, Daniel Basilio, David C. Gadsby, Joshua JC Rosenthal, Ramon Latorre, Miguel Holmgren, Francisco Bezanilla. Laboratorio de Fisiologia Celular, Montemar, Valparaiso, Chile. | ENERGETICS OF THE REACTIONS CONTROLLING THE DEEPLY OCCLUDED STATE OF THE NA+/K+ PUMP 210.24.Ion Motive ATPases |
Poster (3591-Pos, #B452) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| David Medovoy, Luis Cuello, G. Cuello, Eduardo Perozo, Benoit Roux. University of Chicago, Chicago, IL, USA, Texas Tech University Health Sciences Center, Lubbock, TX, USA. | A THREE-ION SELECTIVITY FILTER POTENTIAL ENERGY LANDSCAPE OF A PUTATIVE OPEN-CONDUCTIVE KCSA
210.17.Voltage-gated K Channels: Permeation |
Poster (3433-Pos, #B294) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Mikhail G. Shapiro, Kazuaki Homma, Sebastian Villarreal, Claus-Peter Richter, Francisco Bezanilla. UC Berkeley, Berkeley, CA, USA, University of Chicago, Chicago, IL, USA, Northwestern University, Chicago, IL, USA. | INFRARED LIGHT EXCITES CELLS VIA TRANSIENT CHANGES IN MEMBRANE ELECTRICAL CAPACITANCE.
210.26.Biotechnology & Bioengineering II |
Poster (3646-Pos, #B507) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Ryan Steed, Kristin Trone, Hassane Mchaourab. Vanderbilt University, Nashville, TN, USA. | SUBSTRATE BINDING AND TRANSPORT BY A BACTERIAL MULTIDRUG MFS TRANSPORTER
210.25.Membrane Transport |
Poster (3618-Pos, #B479) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| H. Raghuraman, Qufei Li, Sherry Wanderling, Carlos A. Villalba-Galea, Eduardo Perozo. Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA, Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. | STRUCTURAL DYNAMICS IN THE RESTING AND ACTIVATED STATES OF THE VOLTAGE SENSOR OF Ci-VSP FROM DIPOLAR DISTANCE MEASUREMENTS
210.19.Voltage-gated K Channels: Gating III |
Poster (3475-Pos, #B336) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Giray Enkavi, Emad Tajkhorshid. University of Illinois at Urbana-Champaign, Urbana, IL, USA. | TRANSPORT CYCLE OF MITOCHONDRIAL CARRIERS FROM INTERNAL SYMMETRIES
210.13.Membrane Transporters & Exchangers II |
Poster (3359-Pos, #B220) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Hassane Mchaourab, Johanna Baldus-Becker, Andrea Lakatos, Shruti Sharma, Clemens Glaubitz. Vanderbilt University, Nashville, TN, USA, Goethe University, Frankfurt, Germany. | DYNAMIC NUCLEAR POLARISATION ENHANCED MAS-NMR ON 13C-LEUCINE BOUND TO THE SECONDARY TRANSPORTER LEUT
202.1.Late Poster Presentations |
Poster (L54-Pos, #LB54) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Matthieu Masureel, Smriti Smriti, Chloé Martens, Ping Zou, Jean-Marie Ruysschaert, Hassane Mchaourab, Cédric Govaerts. Université Libre de Bruxelles, Brussels, Belgium, Vanderbilt University Medical Center, Nashville, TN, USA. | STUDYING THE CONFORMATIONAL CYCLE OF THE SECONDARY MULTIDRUG TRANSPORTER LMRP BY EPR SPECTROSCOPY
210.13.Membrane Transporters & Exchangers II |
Poster (3350-Pos, #B211) Wed 2/29, 10:30 AM – 12:30 PM Hall FGH |
| Aaron A. Hoskins, Larry J. Friedman, Daniel J. Crawford, Eric J. Anderson, Inna Shcherbakova, Virginia Cornish, Jeff Gelles, Melissa J. Moore. Univ. Wisconsin, Madison, WI, USA, Brandeis University, Waltham, MA, USA, UMass Medical School/HHMI, Worcester, MA, USA, Columbia University, New York, NY, USA, Department of Biochemistry and Molecular Pharmacology, UMass Medical School/HHMI, Worcester, MA, USA. | INTO THE COSMOS: SINGLE MOLECULE ANALYSIS OF SPLICEOSOME ASSEMBLY AND ACTIVATION
204.Symposium: Dynamics and Localization of RNAs |
Presentation (3099-Symp) Wed 2/29, 1:30 PM – 2:00 PM Ballroom 20D |
| Hector P. Salazar Garcia, Albert Y. Lau, Lydia Blachowicz, Andrew J. Plested, Benoit Roux. Leibniz-Institut für Molekulare Pharmakologie & NeuroCure Initiative, Charité Universitätsmedizin, Berlin, Germany, Johns Hopkins University School of Medicine, Dept. of Biophysics and Biophysical Chemistry, Baltimore, MD, USA, The University of Chicago, Dept. of Biochemistry and Molecular Biology, Chicago, IL, USA. | INTERDIMER CONTACTS PAINT A NEW PICTURE OF GLUTAMATE RECEPTOR ACTIVATION.
206.Platform: Ligand-gated Channels |
Presentation (2112-Plat) Wed 2/29, 2:00 PM – 2:15 PM Ballroom 20BC |
