March 3, 2017 • 9:00am – 6:00pm
Saieh Hall, University of Chicago
In the past few years, a revolution in cryo electron microscopy has taken structural biology by storm. The recent integration of new developments in electron microscopes, direct electron detection cameras, and advances in image analysis methods are allowing the expansion of high resolution structural molecular biology in new and exciting directions by direct visualization of macromolecules and their complexes. The next decades will be dominated by the study of protein-protein, protein-nucleic acid complexes, molecular machines, and their conformational changes in ways that were impossible before due to their size and/or the need to study them in crystalline form. In addition, developments in many aspects of electron microscopy are providing new tools for the study of biological molecules from the single molecule to the cellular level. The Third Coast Workshop on Biological Cryo-EM will address key developments in this fast advancing field and will provide scientists from different disciplines with an opportunity to discuss the state of the field and exchange views from both experimental and computational perspectives.
We are pleased to invite you to the first edition of the NAMD developer workshop jointly organized by the University of Illinois, Urbana-Champaign and the University of Chicago, and to be held on the campus of the University of Chicago.
This workshop is intended to gather the community of NAMD developers for fruitful exchange on current and future developments of the program. It will consist of short presentations aimed at covering practical coding aspects, ongoing developments, architecture specificities, implementations of novel algorithms, as well as broader topics, notably future directions of the program and the parallel programming environment charm++ it uses.
This workshop is not intended for scientific presentations about applications, although illustrative applications of on-going code developments would be welcome.
The workshop will be held at the Gordon Center for Integrative Science on the University of Chicago campus and is sponsored by:
National Institute of General Medical Sciences
NIH Center for Macromolecular Modeling and Bioinformatics (NIH 9P41GM104601)
NIH Hands-on Workshops on Computational Biophysics (NIH 1R25GM103771-01)
The Membrane Protein Structural Dynamics Consortium (NIH grant NIGMS U54-GM087519)
For more information and registration, visit this page.
Francisco Bezanilla, Past President presenting an award to Robert Nakamoto.(Click to enlarge)
The Membrane Protein Structural Dynamics Consortium is always very well represented at the annual Biophysical Society meeting, as can be seen by Klaus Schulten‘s National Lecture in 2015 as well as at the level of participants in a remarkably large number of workshops, symposia, and presentations. This is also reflected in Consortium members being actively involved at the leadership level, including Francisco Bezanilla‘s tenure as Biophysical Society President from 2012 to 2014 and Robert Nakamoto and Olga Boudker‘s service in the current Biophysical Society leadership council.
On August 31, 2015 the Biophysical Society announced that MPSDC Chair Eduardo Perozo was elected as a 2016 Society Fellow. This award honors the Society’s distinguished members who have demonstrated excellence in science, contributed to the expansion of the field of biophysics, and supported the Biophysical Society. The Fellows will be honored at the Awards Ceremony during the Biophysical Society’s 60th Annual Meeting on Monday February 29, 2016 at the Los Angeles Convention Center in Los Angeles, California. Perozo was elected for his leadership and fundamental contributions in ion channel biophysics.
At next year’s meeting in Los Angeles, MPSDC members will participate in a number of specialty symposia and workshops organized by the Biophysical society (more information on the nature of these symposia and workshops can be found on the Biophysical Society meeting website here). We would like to highlight the following in particular (though there are and will certainly be more ways in which Consortium members are involved with the meeting):
- Francisco Bezanilla (University of Chicago) is participating in a symposium on Voltage Sensing and Gating.
- Olga Boudker (Weill Cornell Medical College) is receiving the Michael and Kate Bárány Award during the meeting’s award symposium. During this session, award recipients are recognized and each give a short talk about the work for which they are being recognized. Congratulations, Olga!
- Yifan Cheng (University of California, San Francisco) is co-chairing the Cryo-EM Subgroup 2016 Symposium
- Claudio Grosman(UIUC) is participating in a symposium on Pentameric Ligand-gated Ion Channels: New Insights from Structure and Function.
- Benoît Roux (University of Chicago) is participating in a workshop about Computational Methods for Ion Permeation and Selectivity
- Emad Tajkhorshid (UIUC) will once again be chairing the Permeation & Transport Subgroup 2015 Symposium. He chaired the same subgroup last year.
Last year, MPSDC member and one of our keynote speakers at Frontiers in Membrane Protein Structural Dynamics 2014 Klaus Schulten (UIUC) gave the prestigious National Lecture. The National Lecturer is the highest award given each year by the Biophysical Society. Dr. Schulten’s 2015 National Lecture lecture can be viewed in full here.
See also: interviews from the 59th Biophysical Society Meeting with 2015 National Lecturer Klaus Schulten and Harel Weinstein.
See also: interviews from the 58th Biophysical Society Meeting with Francisco Bezanilla, Past President and Robert Nakamoto, Chair of the 2014 BPS Program Committee.
Structural biology of membrane proteins, particularly from higher eukaryotes, has been transformed in the last two years. New and improved technologies such as electron microscopy and free electron lasers have led to the rapid increase in the number of structures solved and the complexity of these structures. This symposium will highlight advances in technology, celebrate the unprecedented advances in understanding of membrane protein structure and function, and look to the future for this rapidly developing field.
Frontiers in Integral Membrane Protein Structural Biology 2015 is set to take place in Oxford, United Kingdom from October 5th until the 7th.
MPSDC Chair Eduardo Perozo will participate with a lecture titled “Asymmetric Conformational Transition Underlies Mg2+-Driven Gating in CorA.”
Former MPSDC-sponsored Frontiers in Membrane Protein Structural Dynamics conference speakers Robert Stroud (who gave of the two 2014 keynote lectures) and Robert Tampé are also participating.
Learn more about the symposium »
Membrane Proteins: Structure and Function is a conference featuring eight oral sessions and one poster session covering the latest findings across many topics in membrane proteins. It is set to take place on May 11-15, 2015 in Suzhou, China.
The conference was co-organized by MPSDC members Robert Nakamoto (University of Virginia) and Ming Zhou (Baylor College of Medicine). In addition, the following Consortium members are presenting at the conference:
- Volker Dötsch, Goethe Universität Frankfurt
Abstract title:Structure determination of membrane proteins by NMR spectroscopy based on selective labelling approaches and cell-free protein synthesis
- Eduardo Perozo, The University of Chicago
Abstract title:The Structural Basis of Charge Translocation in Voltage Sensing Domains
- Emad Tajkhorshid, University Illinois at Urbana-Champaign
Abstract title:Characterizing Large-scale Conformational Changes in Membrane Transporters at High Spatial and Temporal Resolutions with Advanced Computational Methods
- Francis Valiyaveetil, Oregon Health & Science University
Abstract title:Probing Functional Mechanisms in Ion Channels and Transporters using Unnatural Mutagenesis.
- Ming Zhou, Baylor College of Medicine
Abstract title:Structure of a Mammalian Stearoyl-CoA Desaturase
The program for the MPSDC 2015 Annual Meeting has been posted to the website. Please visit the program page to see the schedule for each day.
MPSDC 2013 Annual Meeting attendees at the Gleacher Center
The Membrane Protein Structural Dynamics (MPSDC) 2015 Annual Meeting website has been launched, and we are ready to receive registrations! Please note that unlike last year’s Frontiers in Membrane Protein Dynamics conference, this annual meeting is open to Consortium participants and invited guests only.
Program at a glance
The Gleacher Center, Chicago IL
DAY 1: Wednesday, April 29th
1:00pm-5:00pm | Workshop: Exploring the Interface Between Computation and Experiment
DAY 2: Thursday, April 30th
8:30am-5:00pm | Scientific Sessions
DAY 3: Friday, May 1st
8:00am-12:30pm | Featured Talks
Francisco Bezanilla, Past President presenting an award to Robert Nakamoto.(Click to enlarge)
The Membrane Protein Structural Dynamics Consortium is always very well represented at the annual Biophysical Society meeting, with Consortium members actively involved at the leadership level, including Francisco Bezanilla‘s tenure as president from 2012 to 2014, as well as at the level of participants in a remarkably large number of workshops, symposia, and presentations.
At next year’s meeting in Baltimore, MPSDC members will participate in a number of specialty symposia and workshops organized by the Biophysical society (more information on the nature of these symposia and workshops can be found on the Biophysical Society meeting website here). We would like to highlight the following in particular (though there are and will certainly be more ways in which Consortium members are involved with the meeting):
- Emad Tajkhorshid (UIUC) will be chairing the Permeation & Transport Subgroup 2015 Symposium. He is also chairing a workshop on Advances in Computing Large Systems.
- Olga Boudker (Weill Cornell Medical College) is chairing a symposium on Neurotransmitter Transporters.
- Christopher Ahern (University of Iowa) is participating in a symposium on Probing Ion Channel Structure/Function Using Novel Tools.
- Jamies Bowie (UCLA) is participating in a workshop on Stabilizing Membrane Proteins.
- Ivet Bahar (UPittsburgh) is giving a lecture titled “Neurotransmitter Translocation: Insights from Network Models and Multiscale Simulations” at the Biopolymers in Vivo Subgroup 2015 Symposium.
- José Faraldo Gómez (NIH and MPSDC Associate Member) is giving a lecture titled “Novel Insights into the Structure and Mechanism of Proton and Sodium/Calcium Exchangers” at the Membrane Biophysics Subgroup 2015 Symposium.
Last but not least, MPSDC member and one of our keynote speakers at Frontiers in Membrane Protein Structural Dynamics 2014 Klaus Schulten (UIUC) will give the prestigious National Lecture. The National Lecturer is the highest award given each year by the Biophysical Society. The recipient presents the National Lecture on Monday evening of the Annual Meeting. We would like to congratulate Dr. Schulten on achieving this great honor.
See also: interviews from last year’s Biophysical Society with Francisco Bezanilla, Past President and Robert Nakamoto, Chair of the 2014 BPS Program Committee.
In collaboration with Anatrace
, we are delighted to announce travel and poster awards for student and postdoctoral fellows attending Frontiers in Membrane Protein Structural Dynamics 2014
Four travel awards ($500) and two poster prizes will be decided on the basis of merit.
Anatrace is a privately owned business which specializes in the production of high-purity detergents, lipids, customs. Well regarded as top performers for membrane protein structural biology, Anatrace products are chosen for their uniquely pure molecules – and the exacting chemistry behind them.
Eligibility: graduate students or post-docs with submitted posters.
How to apply: fill out this form.
Deadline: Friday, May 2nd, 2014.
Announcements about awards will be made during the meeting. If you have any questions, please contact us at firstname.lastname@example.org.
Note: submitting a poster presentation is mandatory for being considered for this award. Student / participant poster abstracts are due by Friday, May 2nd, 2014. You can submit a poster abstract here.
The Membrane Protein Structural Dynamics Consortium (MPSDC) is hosting two workshops on computational modeling and simulation, and spectroscopy methods. These will take place at the University of Chicago campus prior to the conference. Both of these workshops are designed for young investigators to learn some of the cutting edge tools and methodologies that are frequently used in contemporary membrane proteins research.